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YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 in the tumors it remains

SKU: 35507037230

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Description

in the tumors it remains at micromolar concentrations for at least 12 hours

it markedly augments the capacity of HGF at 1

InChiKey: IPEXHQGMTHOKQV-UHFFFAOYSA-N

Smiles: COC1=CC(=CC=C1NC1=NC(NC)=C(Cl)C=N1)C(=O)N1CCOCC1

YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 in the tumors it remainsYM 155, CAS No. 781661 94 7, is a novel survivin suppressant with an IC50 of 0. 54 nM for the inhibition of survivin promoter activity. Sepantronium bromide, also known as YM 155, is a small molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and

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